MIRF research output · UBC

Publications

Peer-reviewed work in nuclear imaging, radiochemistry, drug delivery, and theranostics — from MIRF and collaborators across academia and industry.

63publications

2014–2026year span

10+application areas

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#63

2026¹⁹⁷HgTheranosticsRadiochemistrySPECTDual tracer

Bifunctional sulfur-rich macrocyclic chelators and their immunoconjugates for the targeted delivery of theranostic mercury-197

Randhawa P, Kondo M, Chu ACK, Rodríguez-Rodríguez C, Cai Z, Chan C, Ganga-Sah Y, Chen S, Weatherall N, Davey PRWJ, Merkens H, Reilly RM, Radchenko V, Ramogida CF

RSC Pharm · 2026 · Advance online publication

DOI

#62

2025²⁰³Pb²¹²PbTheranosticsRadiochemistrySPECTDual tracer

Is Thiourea the Weak Link? An Investigation of the In Vitro and In Vivo Destabilization of [203Pb]- and [212Pb]Pb2+ Thiourea-Based Bioconjugates

McNeil BL, Wharton L, Chen CC, Merkens H, Čolović M, Rodríguez-Rodríguez C, Wilson J, Mair S, Zhang C, McDonagh AW, Lin KS, Bénard F, Wuest F, Schaffer P, Ramogida CF

ACS Bio Med Chem Au. · 2025 · Dec 8; 6(1):56-77

DOI

#61

2025¹⁹⁷HgTheranosticsMethodsSPECTDual tracer

Quantitative dual-isotope preclinical SPECT/CT imaging and biodistribution of the mercury-197m/g theranostic pair

Randhawa P, Rodríguez-Rodríguez C, Koniar H, Davey PRWJ, Chen S, Radchenko V, Ramogida CF

EJNMMI Radiopharmacy and Chemistry · 2025 · Advance online publication

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#60

2025⁸⁹Zr¹⁶¹Tb²²⁷ThRadiochemistryCancerPETSPECT

Synthesis and evaluation of HOPO-O8-methyl-tetrazine as a bifunctional chelator for use in [⁸⁹Zr]Zr⁴⁺, [¹⁶¹Tb]Tb³⁺ and [²²⁷Th]Th⁴⁺ radioimmunoconjugates

Carbo-Bague I, Randhawa P, Tosato M, McNeil BL, Čolović M, London L, Rodríguez-Rodríguez C, Osooly M, Wharton L, Merkens H, Van De Voorde M, Ooms M, Yang H, Bénard F, Ramogida CF

Journal of Inorganic Biochemistry · 2025 · 250 · In press

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#59

2025¹¹¹InNanomedicineDrug deliverySPECT

Liposomal lipid nanoparticles for extrahepatic delivery of mRNA

Cheng MHY, Zhang Y, Fox K, Leung J, Strong C, Kang E, Chen Y, Tong M, Bommadevara H, Jan E, Ip OYL, Rodríguez-Rodríguez C, Saatchi K, Häfeli UO, Abdolahzadeh A, Witzigmann D, Cullis PR

Nature Communications · 2025 · 16 · Article 4135

DOI

#58

2025¹¹¹In⁶⁷GaNanomedicineDrug deliveryAntimicrobialPharmacokineticsSPECTDual tracer

Nanogel encapsulation improves pharmacokinetics and biodistribution of antimicrobial peptide LL37 upon lung deposition: In vivo evaluation by SPECT/CT

Kłodzińska SN, Esposito TVF, Agnoletti M, Rodríguez-Rodríguez C, Blackadar C, Wu L, Thakur A, Nahrstedt J, Rades T, Saatchi K, Häfeli UO, Nielsen HM

Journal of Controlled Release · 2025 · Advance online publication

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#57

2025²²⁷ThTheranosticsRadiochemistryCancer

Chelating [²²⁷Th]Th⁴⁺ for peptide receptor radionuclide therapy of neuroendocrine tumours

Wharton L, McNeil SW, Meeres H, Zhang D, Ingham A, Merkens H, Osooly M, Rodríguez-Rodríguez C, Bénard F, Yang H

Bioconjugate Chemistry · 2025 · Advance online publication

DOI

#56

2024¹⁶⁵ErTheranosticsMethodsCancerSPECT

First preclinical SPECT/CT imaging and biodistribution of [¹⁶⁵Er]ErCl₃ and [¹⁶⁵Er]Er-PSMA-617

Saeedi Saghez B, Rodríguez-Rodríguez C, Esquinas PL, Merkens H, Benard F, Radchenko V, Yang H

EJNMMI Radiopharmacy and Chemistry · 2024 · 9 · Article 90

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#55

2024²²⁶AcTheranosticsMethodsSPECT

In vivo quantitative SPECT imaging of actinium-226: feasibility and proof-of-concept

Koniar H, Wharton L, Ingham A, Rodríguez-Rodríguez C, Kunz P, Radchenko V, Yang H, Rahmim A, Uribe C, Schaffer P

Physics in Medicine & Biology · 2024 · 69(15):155003

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#54

2024¹⁵⁵Tb¹⁶¹TbTheranosticsMethodsSPECT

Quantitative SPECT imaging of 155Tb and 161Tb for preclinical theranostic radiopharmaceutical development

Koniar H, McNeil S, Wharton L, Ingham A, Van de Voorde M, Ooms M, Sekar S, Rodríguez-Rodríguez C, Kunz P, Radchenko V, Rahmim A, Uribe C, Yang H, Schaffer P

EJNMMI Physics · 2024 · 11 · Article 77

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#53

2024²²⁶AcTheranosticsMethodsCancerSPECT

Preclinical Evaluation of 226Ac as a Theranostic Agent: Imaging, Dosimetry, and Therapy

Koniar H, Wharton L, Ingham A, Morales Oliver AP, Merkens H, Rodríguez-Rodríguez C, Kunz P, Radchenko V, Yang H, Rahmim A, Uribe C, Schaffer P

Journal of Nuclear Medicine · 2024 · In press

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#52

2024¹⁵⁵Tb¹⁶¹TbTheranosticsCancerRadiochemistrySPECT

Preclinical evaluation of MC1R targeting theranostic pair [155Tb]Tb-crown-αMSH and [161Tb]Tb-crown-αMSH

Wharton L, McNeil SW, Zhang C, Engudar G, Van de Voorde M, Zeisler J, Koniar H, Sekar S, Yuan Z, Schaffer P, Radchenko V, Ooms M, Kunz P, Bénard F, Yang H

Nuclear Medicine and Biology · 2024 · 136–137:108925

DOI

#51

2024¹¹¹In³HNanomedicineDrug deliveryInflammationSPECT

Prodrug Nanomedicine for Synovium Targeted Therapy of Inflammatory Arthritis: Insights from Animal Model and Human Synovial Joint Fluid

Nosrati Z, Chen YA, Bergamo M, Rodríguez-Rodríguez C, Chan J, Shojania K, Kherani RB, Chin C, Kelsall JT, Dehghan N, Colwill AM, Collins D, Saatchi K, Häfeli UO

Advanced Healthcare Materials · 2024 · 2401936

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#50

2024⁶⁷GaAntimicrobialPharmacokineticsDrug deliverySPECT

Biodistribution of the cationic host defense peptide LL-37 using SPECT/CT

Esposito TVF, Rodríguez-Rodríguez C, Blackadar C, Kłodzińska S, Mørck Nielsen H, Saatchi K, Häfeli UO

European Journal of Pharmaceutics and Biopharmaceutics · 2024 · 114398

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#49

2024⁶⁷GaAntimicrobialNanomedicinePharmacokineticsSPECT

Biodistribution of native and nano-formulated Innate Defense Regulator (IDR) peptide 1002

Esposito TVF, Blackadar C, Wu L, Rodríguez-Rodríguez C, Haney EF, Pletzer D, Saatchi K, Hancock REW, Häfeli UO

Molecular Pharmaceutics · 2024 · 21:2751–2766

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#48

2024^99mTcMethodsRadiochemistrySPECT

Development of a 99mTc-labeled tetrazine for pretargeted SPECT imaging using an alendronic acid-based bone targeting model

Bohrmann L, Poulie CBM, Rodríguez-Rodríguez C, Karagiozov S, Saatchi K, Herth MM, Häfeli UO

PLoS ONE · 2024 · 19(4):e0300466

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#47

2024¹¹¹InDrug deliveryInflammationSPECT

Intranasal delivery of low-dose anti-CD124 antibody enhances the treatment of chronic rhinosinusitis with nasal polyps

Wu J, Jones N, Chao PH, Chan V, Hohenwarter L, Wu A, Bergamo M, Rodríguez-Rodríguez C, Saatchi K, Liang A, Häfeli UO, Tan Z, Hedtrich S, Andrew LJ, Li SD

Biomaterials · 2024 · 308:122567

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#46

2024¹²³IDrug deliveryRadiochemistrySPECT

A Novel Leu-Enkephalin Prodrug Produces Pain-Relieving and Antidepressant Effects

Hohenwarter L, Puil E, Rouhollahi E, Bohrmann L, Lu S, Saatchi K, Häfeli UO, Barr A, Bottger R, DurgaRao Viswanadham KK, Li SD

Molecular Pharmaceutics · 2024 · 21(2):688–703

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#45

2024CancerMethodsOpticalUS

Development of an Immunosuppressed Orthotopic Hepatocellular Carcinoma Rat Model for the Evaluation of Chemo- and Radioembolization Therapies

Charles L, Sekar S, Osooly M, Javed S, Williams KC, Welch I, Barta I, Saatchi K, Häfeli UO

European Journal of Pharmaceutics and Biopharmaceutics · 2024 · 196:114180

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#44

2023⁶⁸GaPharmacokineticsMethodsPET

Preclinical PET Imaging and Toxicity Study of a 68Ga-Functionalized Polymeric Cardiac Blood Pool Agent

Saatchi K, Benard F, Hundal N, Grimes J, Shcherbinin S, Pourghiasian M, Brooks DE, Celler A, Häfeli UO

Pharmaceutics · 2023 · 15:767

DOI

#43

2023¹¹¹InNanomedicineDrug deliverySPECT

Pulmonary delivery of siRNA-loaded lipid-polymer hybrid nanoparticles: Effect of nanoparticle size

Wadhwa A, Bobak TR, Bohrmann L, Geczy R, Sekar S, Sathyanarayanan G, Kutter JP, Franzyk H, Foged C, Saatchi K, Häfeli UO

OpenNano · 2023 · 13:100180

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#42

2023²²⁵Ac¹⁵⁵TbTheranosticsRadiochemistrySPECT

Rearmed Bifunctional Chelating Ligand for 225Ac/155Tb Precision-Guided Theranostic Radiopharmaceuticals─H4noneunpaX

Wharton L, Yang H, Jaraquemada-Peláez M de G, Merkens H, Engudar G, Ingham A, Koniar H, Radchenko V, Kunz P, Schaffer P, Bénard F, Orvig C

Journal of Medicinal Chemistry · 2023 · 66(19):13705–13730

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#41

2023¹¹¹InNanomedicineCancerMethodsSPECT

Quantitative Evaluation of a Multimodal Aptamer-Targeted Long-Circulating Polymer for Tumor Targeting

Bohrmann L, Burghardt T, Rodríguez-Rodríguez C, Herth MM, Saatchi K, Häfeli UO

ACS Omega · 2023

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#40

2023¹⁵⁵Tb¹⁶¹TbTheranosticsCancerRadiochemistrySPECT

Preclinical evaluation of [155/161Tb]Tb-Crown-TATE — A novel SPECT imaging theranostic agent targeting neuroendocrine tumours

Wharton L, McNeil SW, Merkens H, Yuan Z, Van de Voorde M, Engudar G, Ingham A, Koniar H, Rodríguez-Rodríguez C, Radchenko V, Ooms M, Kunz P, Bénard F, Schaffer P, Yang H

Molecules · 2023 · 28(7):3155

DOI

#39

2022¹¹¹InTheranosticsMethodsMRIOpticalSPECTUSCT

Aptamers used for molecular imaging and theranostics — recent developments

Bohrmann L, Burghardt T, Haynes C, Saatchi K, Häfeli UO

Theranostics · 2022 · 12:4010–4050

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#38

2022^99mTcDrug deliveryMethodsOpticalSPECT

Potential of Nuclear Imaging Techniques to Study the Oral Delivery of Peptides

Saxena T, Sie C, Lin K, Ye D, Saatchi K, Häfeli UO

Pharmaceutics · 2022 · 14:2809

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#37

2022²²⁵Ac¹¹¹InTheranosticsRadiochemistrySPECT

H4picoopa ─ Robust Chelate for 225Ac/111In Theranostics

Wharton L, Jaraquemada-Peláez M de G, Zhang C, Zeisler J, Rodríguez-Rodríguez C, Osooly M, Radchenko V, Yang H, Lin KS, Bénard F, Schaffer P, Orvig C

Bioconjugate Chemistry · 2022 · 33(10):1900–1921

DOI

#36

2022⁶⁷GaAntimicrobialPharmacokineticsSPECT

Biodistribution and toxicity of innate defense regulator 1018 (IDR-1018)

Esposito TVF, Rodríguez-Rodríguez C, Blackadar C, Haney EF, Pletzer D, Hancock REW, Saatchi K, Häfeli UO

European Journal of Pharmaceutics and Biopharmaceutics · 2022 · 179:11–25

DOI

#35

2022²²⁵Ac²²⁶AcTheranosticsMethodsSPECT

SPECT imaging of 226Ac as a theranostic isotope for 225Ac radiopharmaceutical development

Koniar H, Rodríguez-Rodríguez C, Radchenko V, Yang H, Kunz P, Rahmim A, Uribe C, Schaffer P

Physics in Medicine and Biology · 2022 · 67(18):185009

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#34

2022¹¹¹AgAntimicrobialNanomedicineSPECT

SPECT/CT Imaging of 111Ag for the Preclinical Evaluation of Silver-Based Antimicrobial Nanomedicines

Blackadar C, Choi K-Y G, Embree MF, Hennkens HM, Rodríguez-Rodríguez C, Hancock REW, Saatchi K, Häfeli UO

ACS Applied Materials & Interfaces · 2022 · 14(23):26382–26393

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#33

2022²¹³Bi¹¹¹InTheranosticsCancerRadiochemistrySPECT

[213Bi]Bi3+/[111In]In3+-neunpa-cycMSH: Theranostic Radiopharmaceutical Targeting Melanoma ─ Structural, Radiochemical, and Biological Evaluation

Wharton L, Zhang C, Yang H, Zeisler J, Radchenko V, Rodríguez-Rodríguez C, Ossoly M, Patrick OB, Lin KS, Bénard F, Schaffer P, Orvig C

Bioconjugate Chemistry · 2022 · 33(3):505–522

DOI

#32

2022²²⁵Ac¹¹¹InTheranosticsRadiochemistrySPECT

H3TPAN-Triazole-Bn-NH2: Tripicolinate Clicked-Bifunctional Chelate for [225Ac]/[111In] Theranostics

Wharton L, Zhang C, Zeisler J, Rodríguez-Rodríguez C, Osooly M, Radchenko V, Yang H, Lin KS, Bénard F, Schaffer P, Orvig C

Bioconjugate Chemistry · 2022 · 33(12):2381–2397

DOI

#31

2022¹¹¹InDrug deliveryPharmacokineticsSPECT

Metal-ion coordinated self-assembly of human insulin directs kinetics of insulin release as determined by preclinical SPECT/CT imaging

Engudar G, Rodríguez-Rodríguez C, Mishra NK, Bergamo M, Amouroux G, Jensen KJ, Saatchi K, Häfeli UO

Journal of Controlled Release · 2022 · 343:347–360

DOI

#30

2021¹⁷⁷LuTheranosticsCancerNanomedicine

Electron microscopy of antibody-conjugated, lutetium-177 lanthanide gold-coated nanoparticles: Proof of concept of targeted loci—A potential theranostic agent

Kogos B, Cohen-Gould L, Rodríguez-Rodríguez C, Sossi V, Sobol N, Johnson R, Miller DC, Robertson JD, Pevsner PH

AIP Advances · 2021 · 11(4):045035

DOI

#29

2021MethodsCT

Comparison of Rhenium and Iodine as Contrast Agents in X-Ray Imaging

de la Vega JC, Esquinas PL, Gill JK, Jessa S, Gill B, Thakur Y, Saatchi K, Häfeli UO

Contrast Media & Molecular Imaging · 2021 · 1250360

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#28

2021¹²³I¹²⁵IMethodsDrug deliverySPECTDual tracer

Simultaneous SPECT imaging with 123I and 125I — a practical approach to assessing a drug and its carrier at the same time with dual imaging

Nosrati Z, Esquinas PL, Rodríguez-Rodríguez C, Tran T, Maharaj A, Saatchi K, Häfeli UO

International Journal of Pharmaceutics · 2021 · 606:120884

DOI

#27

2021¹¹¹InNanomedicineDrug delivery

Poly(lactide-co-glycolide) Nanoparticles Mediate Sustained Gene Silencing and Improved Biocompatibility of siRNA Delivery Systems in Mouse Lungs after Pulmonary Administration

Wu L, Wu LP, Wu J, Sun J, He Z, Rodríguez-Rodríguez C, Saatchi K, Dailey LA, Häfeli UO, Dongmei C, Mingshi Y

ACS Applied Materials & Interfaces · 2021 · 13:3722–3737

DOI

#26

2021¹¹¹InMethods

Preparation of Heat-Denatured Macroaggregated Albumin for Biomedical Applications Using a Microfluidics Platform

Esposito TVF, Stütz H, Rodríguez-Rodríguez C, Bergamo M, Charles L, Geczy R, Saatchi K, Häfeli UO

ACS Biomaterials Science & Engineering · 2021 · 7(6):2823–2834

DOI

#25

2021¹¹¹In⁶⁴CuNanomedicineImagingPETSPECT

Hybrid Metal–Phenol Nanoparticles with Polydopamine-like Coating for PET/SPECT/CT Imaging

Suárez-García S, Esposito TVF, Neufeld-Peters J, Bergamo M, Yang H, Saatchi K, Schaffer P, Häfeli UO, Ruiz-Molina D, Rodríguez-Rodríguez C, Novio F

ACS Applied Materials & Interfaces · 2021 · 13:10705–10718

DOI

#24

2020InflammationMethodsIR

Refinement and validation of infrared thermal imaging (IRT): a non-invasive technique to measure disease activity in a mouse model of rheumatoid arthritis

Nosrati Z, Bergamo M, Rodríguez-Rodríguez C, Saatchi K, Häfeli UO

2020

DOI

#23

2020¹¹¹InDrug deliveryPharmacokineticsSPECTCT

Bioimaging and Biodistribution of the Metal-Ion-Controlled Self-Assembly of PYY3-36 Studied by SPECT/CT

Kalomoiri P, Rodríguez-Rodríguez C, Sørensen KK, Bergamo M, Saatchi K, Häfeli UO, Jensen KJ

ChemBioChem · 2020 · 248

DOI

#22

2020²²⁵AcTheranosticsRadiochemistryCancer

Synthesis and Evaluation of a Macrocyclic Actinium-225 Chelator, Quality Control and In Vivo Evaluation of 225Ac-crown-αMSH Peptide

Yang H, Zhang C, Yuan Z, Rodríguez-Rodríguez C, Robertson A, Radchenko V, Perron R, Gendron D, Causey P, Gao F, Bénard F, Schaffer P

Chemistry – A European Journal · 2020 · 26(50):11435–11440

DOI

#21

2020⁶⁷Ga⁶⁸GaRadiochemistryPET

H2CHXhox: Rigid Cyclohexane-Reinforced Nonmacrocyclic Chelating Ligand for [nat/67/68Ga]Ga3+

Wang X, Jaraquemada-Peláez M de G, Cao Y, Ingham A, Rodríguez-Rodríguez C, Pan J, Wang Y, Saatchi K, Häfeli UO, Lin K-S, Orvig C

Inorganic Chemistry · 2020 · 59(7):4895–4908

DOI

#20

2020¹¹¹InNanomedicineDrug deliveryPharmacokineticsSPECT

Monosized Polymeric Microspheres Designed for Passive Lung Targeting: Biodistribution and Pharmacokinetics after Intravenous Administration

Agnoletti M, Rodríguez-Rodríguez C, Klodzinska SN, Esposito TVF, Saatchi K, Nielsen HM, Häfeli UO

ACS Nano · 2020 · 14:6693–6706

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#19

2020¹¹¹InNanomedicineDrug deliveryMethodsSPECT

Quantitative comparison of three widely-used pulmonary administration methods in vivo with radiolabeled inhalable nanoparticles

Wu L, Rodríguez-Rodríguez C, Cun D, Yang M, Saatchi K, Häfeli UO

European Journal of Pharmaceutics and Biopharmaceutics · 2020 · 152:108–115

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#18

2020¹²⁵I¹²³IDrug deliveryPharmacokineticsSPECTDual tracer

Using in vitro lipolysis and SPECT/CT in vivo imaging to understand oral absorption of fenofibrate from lipid-based drug delivery systems

Tran T, Bønløkke P, Rodríguez-Rodríguez C, Nosrati Z, Esquinas PL, Borkar N, Plum J, Strindberg S, Karagiozov S, Rades T, Müllertz A, Saatchi K, Häfeli UO

Journal of Controlled Release · 2020 · 317:375–384

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#17

2019⁸⁹ZrRadiochemistryPharmacokineticsPET

Evaluation of the Tetrakis(3-Hydroxy-4-Pyridinone) Ligand THPN with Zirconium(IV): Thermodynamic Solution Studies, Bifunctionalization, and in Vivo Assessment of Macromolecular 89Zr-THPN-Conjugates

Buchwalder C, Jaraquemada-Peláez M de G, Rousseau J, Merkens H, Rodríguez-Rodríguez C, Orvig C, Bénard F, Schaffer P, Saatchi K, Häfeli UO

Inorganic Chemistry · 2019 · 58(21):14667–14681

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#16

2019²²⁵AcTheranosticsCancerRadiochemistry

Evaluation of polydentate picolinic acid chelating ligands and an α-melanocyte-stimulating hormone derivative for targeted alpha therapy using ISOL-produced 225Ac

Ramogida CF, Robertson AKH, Jermilova U, Zhang C, Yang H, Kunz P, Lassen J, Bratanovic I, Brown V, Southcott L, Rodríguez-Rodríguez C, Radchenko V, Bénard F, Orvig C, Schaffer P

EJNMMI Radiopharmacy and Chemistry · 2019

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#15

2019¹⁸⁸ReCancerTheranosticsMethodsSPECT

Radioembolization of Hepatocellular Carcinoma with Built-In Dosimetry: First In Vivo Results with Uniformly-Sized, Biodegradable Microspheres Labeled with 188Re

de la Vega J, Esquinas PL, Rodríguez-Rodríguez C, Bokharaei M, Moskalev I, Liu D, Saatchi K, Häfeli UO

Theranostics · 2019 · 9:868–883

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#14

2018¹¹¹In⁶⁷GaAntimicrobialDrug deliverySPECTCTDual tracer

Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses on Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization

Thakur A, Rodríguez-Rodríguez C, Saatchi K, Rose F, Esposito T, Nosrati Z, Andersen P, Christensen D, Häfeli UO, Foged C

Frontiers in Immunology · 2018 · 9:2825

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#13

2018¹¹¹In⁶⁷GaMethodsPharmacokineticsSPECTDual tracer

Dual SPECT Imaging of 111In and 67Ga to simultaneously Determine In Vivo the Pharmacokinetics of Different Radiopharmaceuticals: A Quantitative Tool in Preclinical Research

Esquinas P, Rodríguez-Rodríguez C, Esposito T, Saatchi K, Celler A, Sossi V, Häfeli UO

Physics in Medicine & Biology · 2018 · 63:235029

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#12

2018¹¹¹InRadiochemistrySPECT

H4octox: Versatile Bimodal Octadentate Acyclic Chelating Ligand for Medicinal Inorganic Chemistry

Wang X, Jaraquemada-Peláez M de G, Rodríguez-Rodríguez C, Cao Y, Buchwalder C, Choudhary N, Jermilova U, Ramogida CF, Saatchi K, Häfeli UO, Patrick BO, Orvig C

Journal of the American Chemical Society · 2018 · 140:15487–15500

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#11

2018¹⁷⁷LuTheranosticsCancerNanomedicineSPECT

Synthesis and targeting of gold-coated 177Lu-containing lanthanide phosphate nanoparticles — A potential theranostic agent for pulmonary metastatic disease

Sobol N, Sutherlin L, Cedrowska E, Schorp J, Rodríguez-Rodríguez C, Sossi V, Lattimer J, Miller DC, Pevsner P, Robertson JD

APL Bioengineering · 2018 · 2(1):016101

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#10

2018²⁰⁹At²¹¹AtTheranosticsMethodsSPECT

Evaluation of 209At as a theranostic isotope for 211At-radiopharmaceutical development using high-energy SPECT

Crawford JR, Robertson AKH, Yang H, Rodríguez-Rodríguez C, Esquinas PL, Kunz P, Blinder S, Sossi V, Schaffer P, Ruth TJ

Physics in Medicine & Biology · 2018 · 63(4):045025

DOI

2018⁶⁷GaNanomedicineCancerPharmacokineticsSPECT

Quantitative SPECT imaging and biodistribution point to molecular weight independent tumor uptake for some long-circulating polymer nanocarriers

Schmitt V, Rodríguez-Rodríguez C, Hamilton JL, Shenoi RA, Schaffer P, Sossi V, Kizhakkedathu JN, Saatchi K, Häfeli UO

RSC Advances · 2018 · 8(10):5586–5595

DOI

2017²²⁵AcTheranosticsRadiochemistry

An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy

Thiele NA, Brown V, Kelly JM, Amor-Coarasa A, Jermilova U, MacMillan SN, Nikolopoulou A, Ponnala S, Ramogida CF, Robertson AKH, Rodríguez-Rodríguez C, Schaffer P, Williams C Jr, Babich JW, Radchenko V, Wilson JJ

Angewandte Chemie International Edition · 2017 · 56(46):14712–14717

DOI

2017⁸⁹ZrRadiochemistryPET

A new tetrapodal 3-hydroxy-4-pyridinone ligand for complexation of 89zirconium for positron emission tomography (PET) imaging

Buchwalder C, Rodríguez-Rodríguez C, Schaffer P, Karagiozov SK, Saatchi K, Häfeli UO

Dalton Transactions · 2017 · 46(29):9654–9663

DOI

2017¹⁸⁸ReTheranosticsMethodsSPECTCT

Accuracy of Rhenium-188 SPECT/CT activity quantification for applications in radionuclide therapy using clinical reconstruction methods

Esquinas P, Uribe C, Gonzales M, Rodríguez-Rodríguez C, Häfeli UO, Celler A

Physics in Medicine & Biology · 2017 · 62:6379–6396

DOI

2017¹⁸⁸ReMethodsImagingSPECT

188Re image performance assessment using small animal multi-pinhole SPECT/PET/CT system

Esquinas PL, Rodríguez-Rodríguez C, De La Vega JC, Bokharaei M, Saatchi K, Shirmohammad M, Häfeli UO, Sossi V, Celler A

Physica Medica · 2017 · 33:26–37

DOI

2017²²⁵AcTheranosticsMethods

Multi-isotope SPECT imaging of the 225Ac decay chain: feasibility studies

Robertson AKH, Ramogida CF, Rodríguez-Rodríguez C, Blinder S, Kunz P, Sossi V, Schaffer P

Physics in Medicine & Biology · 2017 · 62(11):4406

DOI

2017NanomedicineDrug delivery

Characterization of Alendronic- and Undecylenic Acid Coated Magnetic Nanoparticles for the Targeted Delivery of Rosiglitazone to Subcutaneous Adipose Tissue

Saatchi K, Tod SE, Leung D, Nicholson KE, Andreu I, Buchwalder C, Schmitt V, Häfeli UO

Nanomedicine: Nanotechnology, Biology, and Medicine · 2017 · 13(2):559–568

DOI

2016¹⁸⁸ReMethodsImaging

Accuracy, Reproducibility and Uncertainty Analysis of Thyroid Probe-Based Activity Measurements for Determination of Dose Calibrator Settings

Esquinas P, Tanguay JF, Gonzalez M, Vuckovic M, Rodríguez-Rodríguez C, Häfeli UO, Celler A

Medical Physics · 2016 · 43(12):6309–6321

DOI

2014¹⁸FMethodsImagingPETSPECT

Performance Assessment of a Preclinical PET Scanner with Pinhole Collimation by Comparison to a Coincidence-Based Small-Animal PET Scanner

Walker M, Goorden M, Dinelle K, Ramakers R, Blinder S, Shirmohammad M, van der Have F, Beekman F, Sossi V

Journal of Nuclear Medicine · 2014 · 55(8):1368–1374

DOI