49. Esposito TVF, Rodriguez-Rodriguez C, Blackadar C, Kłodzińska S, Mørck Nielsen H., Saatchi K, Hafeli UO (2024). Biodistribution of the cationic host defense peptide LL-37 using SPECT/CT. European Journal of Pharmaceutics and Biopharmaceutics, 114398

48. Esposito TVF, Blackadar C, Wu L, Rodriguez-Rodriguez C, Haney EF, Pletzer D, Saatchi K, Hancock REW, Hafeli UO (2024). Biodistribution of native and nano-formulated Innate Defense Regulator (IDR) peptide 1002. Mol Pharm, 21, 2751-2766

47. Bohrmann L, Poulie CBM, Rodríguez-Rodríguez C, Karagiozov S, Saatchi K, Herth MM, et al. (2024) Development of a 99mTc-labeled tetrazine for pretargeted SPECT imaging using an alendronic acid-based bone targeting model. PLoS ONE 19(4), e0300466

46. Wu J, Jones N, Chao PH, Chan V, Hohenwarter L, Wu A, Bergamo M, Rodríguez-Rodríguez C, Saatchi K, Liang A, Häfeli UO, Tan Z, Hedtrich S, Andrew LJ, Li SD (2024). Intranasal delivery of low-dose anti-CD124 antibody enhances the treatment of chronic rhinosinusitis with nasal polyps. Biomaterials 308, 122567

45. Hohenwarter L, Puil E, Rouhollahi E, Bohrmann L, Lu S, Saatchi K, Häfeli UO, Barr A, Bottger R, DurgaRao Viswanadham KK, Li SD (2024). A Novel Leu-Enkephalin Prodrug Produces Pain-Relieving and Antidepressant Effects. Mol Pharm 21 (2), 688-703

44. Charles L, Sekar S, Osooly M, Javed S, Williams KC, Welch I, Barta I, Saatchi K, Häfeli UO (2024). Development of an Immunosuppressed Orthotopic Hepatocellular Carcinoma Rat Model for the Evaluation of Chemo- and Radioembolization Therapies. Europ J Pharm Biopharm 196, 114180

43. Saatchi K, Benard F, Hundal N, Grimes J, Shcherbinin S, Pourghiasian M, Brooks DE, Celler A, Häfeli UO (2023). Preclinical PET Imaging and Toxicity Study of a 68Ga-Functionalized Polymeric Cardiac Blood Pool Agent. Pharmaceutics 15, 767

42. Wadhwa A, Bobak TR, Bohrmann L, Geczy R, Sekar S, Sathyanarayanan G, Kutter JP, Franzyk H, Foged C, Saatchi K, Häfeli UO (2023). Pulmonary delivery of siRNA-loaded lipid-polymer hybrid nanoparticles: Effect of nanoparticle size. OpenNano 13, 100180

41. Wharton, L., Yang, H., Jaraquemada-Peláez, M. de G., Merkens, H., Engudar, G., Ingham, A., et al. (2023). Rearmed Bifunctional Chelating Ligand for 225Ac/155Tb Precision-Guided Theranostic Radiopharmaceuticals─H4noneunpaX. J. Med. Chem., 66(19), 13705–13730. http://doi.org/10.1021/acs.jmedchem.3c01151

40. Bohrmann, L., Burghardt, T., Rodríguez-Rodríguez, C., Herth, M. M., Saatchi, K., Häfeli, U. O. (2023). Quantitative Evaluation of a Multimodal Aptamer-Targeted Long-Circulating Polymer for Tumor Targeting. ACS Omega, 1–18. http://doi.org/10.1021/acsomega.2c07762

39. Wharton, L., McNeil, S. W., Merkens, H., Yuan, Z., Van de Voorde, M., Engudar, G., Ingham, A., Koniar, H., Rodríguez-Rodríguez, C., Radchenko, V., Ooms, M., Kunz, P., Bénard, F., Schaffer, P., & Yang, H. (2023). Preclinical evaluation of [155/161Tb]Tb-Crown-TATE—A novel SPECT imaging theranostic agent targeting neuroendocrine tumours. Molecules, 28(7), 3155. http://doi.org/10.3390/molecules28073155

38. Bohrmann L., Burghardt T., Haynes C., Saatchi K., Häfeli U.O. (2022). Aptamers used for molecular imaging and theranostics – recent developments. Theranostics 12, 4010-4050

37. Saxena T., Sie C., Lin K., Ye D., Saatchi K., Häfeli U.O. (2022). Potential of Nuclear Imaging Techniques to Study the Oral Delivery of Peptides. Pharmaceutics 14, 2809, 1-23

36. Wharton, L., Jaraquemada-Peláez, M. de G., Zhang, C., Zeisler, J., Rodríguez-Rodríguez, C., Osooly, M., Radchenko V., Yang H., Lin K-S. , Bénard F., Schaffer P., Orvig C. (2022). H4picoopa─Robust Chelate for 225Ac/111In Theranostics. Bioconjugate Chemistry, 33(10), 1900–1921, http://doi.org/10.1021/acs.bioconjchem.2c00364

35. Esposito, T. V. F., Rodríguez-Rodríguez, C., Blackadar, C., Haney, E. F., Pletzer, D., Hancock, R. E. W., Saatchi, K., Häfeli, U. O. (2022). Biodistribution and toxicity of innate defense regulator 1018 (IDR-1018). European Journal of Pharmaceutics and Biopharmaceutics, 179, 11–25. http://doi.org/10.1016/j.ejpb.2022.08.004

34. Koniar, H., Rodríguez-Rodríguez, C., Radchenko, V., Yang, H., Kunz, P., Rahmim, A., Uribe, C., Schaffer, P. (2022). SPECT imaging of 226Ac as a theranostic isotope for 225Ac radiopharmaceutical development. Physics in Medicine and Biology, 67(18), 185009. http://doi.org/10.1088/1361-6560/ac8b5f

33. Blackadar, C., Choi, K.-Y. G., Embree, M. F., Hennkens, H. M., Rodríguez-Rodríguez, C., Hancock, R. E. W., Saatchi, K., Häfeli, U. O. (2022). SPECT/CT Imaging of 111Ag for the Preclinical Evaluation of Silver-Based Antimicrobial Nanomedicines. ACS Applied Materials & Interfaces, 14, 23, 26382–26393. http://doi.org/10.1021/acsami.2c03609

32. Wharton, L., Zhang, C., Yang, H., Zeisler, J., Radchenko, V., Rodríguez-Rodríguez, C., Ossoly, M., Patrick, O.B., Lin K-S. , Bénard F., Schaffer P., Orvig C. (2022). [213Bi]Bi3+/[111In]In3+-neunpa-cycMSH: Theranostic Radiopharmaceutical Targeting Melanoma─Structural, Radiochemical, and Biological Evaluation. Bioconjugate Chemistry, 33(3), 505–522. http://doi.org/10.1021/acs.bioconjchem.2c00038

31. Wharton, L., Zhang, C., Zeisler, J., Rodríguez-Rodríguez, C., Osooly, M., Radchenko V., Yang H., Lin K-S. , Bénard F., Schaffer P., Orvig C. (2022). H3TPAN-Triazole-Bn-NH2: Tripicolinate Clicked-Bifunctional Chelate for [225Ac]/[111In] Theranostics. Bioconjugate Chem., 33, 12, 2381–2397. http://doi.org/10.1021/acs.bioconjchem.2c00465

30. Engudar, G., Rodríguez-Rodríguez, C., Mishra, N. K., Bergamo, M., Amouroux, G., Jensen, K. J., Saatchi, K., Häfeli, U. O. (2022). Metal-ion coordinated self-assembly of human insulin directs kinetics of insulin release as determined by preclinical SPECT/CT imaging. Journal of Controlled Release : Official Journal of the Controlled Release Society, 343, 347–360. http://doi.org/10.1016/j.jconrel.2022.01.032

29. de la Vega JC, Esquinas PL, Gill JK, Jessa S, Gill B, Thakur Y, Saatchi K, Häfeli UO (2021). Comparison of Rhenium and Iodine as Contrast Agents in X-Ray Imaging. Contrast Media Mol Imaging, 1250360

28. Nosrati, Z., Esquinas, P. L., Rodríguez-Rodríguez, C., Tran, T., Maharaj, A., Saatchi, K., Häfeli, U. O. (2021). Simultaneous SPECT imaging with 123I and 125I – a practical approach to assessing a drug and its carrier at the same time with dual imaging. International Journal of Pharmaceutics, 606, 120884. http://doi.org/10.1016/j.ijpharm.2021.120884

27. Wu, L., Wu, L.-P., Wu, J., Sun, J., He, Z., Rodríguez-Rodríguez, C., Saatchi, K., Dailey, L.A., Häfeli, U. O., Dongmei C., Mingshi, Y. (2021). Poly(lactide-co-glycolide) Nanoparticles Mediate Sustained Gene Silencing and Improved Biocompatibility of siRNA Delivery Systems in Mouse Lungs after Pulmonary Administration, ACS Applied Materials & Interfaces. 13, 3722 – 3737, http://doi.org/10.1021/acsami.0c21259

26. Esposito, T. V. F., Stütz, H., Rodríguez-Rodríguez, C., Bergamo, M., Charles, L., Geczy, R., Saatchi, K., Häfeli, U. O. (2021). Preparation of Heat-Denatured Macroaggregated Albumin for Biomedical Applications Using a Microfluidics Platform. ACS Biomaterials Science & Engineering, 7(6), 2823–2834. http://doi.org/10.1021/acsbiomaterials.1c00284

25. Suárez-García, S., Esposito, T. V. F., Neufeld-Peters, J., Bergamo, M., Yang, H., Saatchi, K., Schaffer, P., Häfeli, U. O., Ruiz-Molina, D.*, Rodríguez-Rodríguez, C.*, Novio, F.* (2021). Hybrid Metal–Phenol Nanoparticles with Polydopamine-like Coating for PET/SPECT/CT Imaging. ACS Applied Materials & Interfaces. 13, 10705-10718 http://doi.org/10.1021/acsami.0c20612

24. Nosrati, Z., Bergamo, M., Rodríguez-Rodríguez, C., Saatchi, K., & Häfeli, U. O. (2020). Refinement and validation of infrared thermal imaging (IRT): a non-invasive technique to measure disease activity in a mouse model of rheumatoid arthritis, 1–16. http://doi.org/10.1186/s13075-020-02367-w

23. Kalomoiri, P., Rodríguez-Rodríguez, C., Sørensen, K. K., Bergamo, M., Saatchi, K., Häfeli, U. O., & Jensen, K. J. (2020). Bioimaging and Biodistribution of the Metal-Ion-Controlled Self-Assembly of PYY3-36 Studied by SPECT/CT. Chembiochem : a European Journal of Chemical Biology, 248. http://doi.org/10.1002/cbic.202000266

22. Yang, H., Zhang, C., Yuan, Z., Rodríguez-Rodríguez, C., Robertson, A., Radchenko, V., et al. (2020). Synthesis and Evaluation of a Macrocyclic Actinium-225 Chelator, Quality Control and In Vivo Evaluation of 225 Ac-crown-αMSH Peptide. Chemistry (Weinheim an Der Bergstrasse, Germany), 26(50), 11435–11440. http://doi.org/10.1002/chem.202002999

21. Wang, X., Jaraquemada-Peláez, M. de G., Cao, Y., Ingham, A., Rodríguez-Rodríguez, C., Pan, J., et al. (2020). H2CHXhox: Rigid Cyclohexane-Reinforced Nonmacrocyclic Chelating Ligand for [nat/67/68Ga]Ga3. Inorganic Chemistry, 59(7), 4895–4908. http://doi.org/10.1021/acs.inorgchem.0c00168

20. Agnoletti, M., Rodríguez-Rodríguez C., Klodzinska, S.N., Esposito, T.V.F., Saatchi, K., Nielsen, H. M., Hafeli, U.O.(2020) Monosized Polymeric Microspheres Designed for Passive Lung Targeting: Biodistribution and Pharmacokinetics after Intravenous Administration. ACS Nano, 14, 6693-6706

19. Wu, L., Rodríguez-Rodríguez C., Cun, D., Yang, M., Saatchi, K., & Hafeli, U. O. (2020). Quantitative comparison of three widely-used pulmonary administration methods in vivo with radiolabeled inhalable nanoparticles.European Journal of Pharmaceutics and Biopharmaceutics, 152, 108-115. http://doi.org/10.1016/j.ejpb.2020.05.004

18. Tran, T., Bønløkke, P., Rodríguez-Rodríguez C., Nosrati, Z., Esquinas, P. L., Borkar, N., et al. (2020).Using in vitro lipolysis and SPECT/CT in vivo imaging to understand oral absorption of fenofibrate from lipid-based drug delivery systems. Journal of Controlled Release : Official Journal of the Controlled Release Society, 317, 375-384. http://doi.org/10.1016/j.jconrel.2019.11.024

17. Buchwalder, C., Jaraquemada-Peláez, M. de G., Rousseau, J., Merkens, H., Rodríguez-Rodríguez C., Orvig, C., et al. (2019). Evaluation of the Tetrakis(3-Hydroxy-4-Pyridinone) Ligand THPN with Zirconium(IV): Thermodynamic Solution Studies, Bifunctionalization, and in Vivo Assessment of Macromolecular 89Zr-THPN-Conjugates. Inorganic Chemistry 58(21), 14667-14681. http://doi.org/10.1021/acs.inorgchem.9b02350

16. Ramogida, C. F., Robertson, A. K. H., Jermilova, U., Zhang, C., Yang, H., Kunz, P., et al. (2019). Evaluation of polydentate picolinic acid chelating ligands and an α-melanocyte-stimulating hormone derivative for targeted alpha therapy using ISOL-produced 225Ac,1-20. http://doi.org/10.1186/s41181-019-0072-5
15. de la Vega J, Esquinas PL, Rodriguez-Rodriguez C, Bokharaei M, Moskalev I, Liu D, Saatchi K, Hafeli UO (2019). Radioembolization of Hepatocellular Carcinoma with Built-In Dosimetry: First In Vivo Results with Uniformly-Sized, Biodegradable Microspheres Labeled with 188Re. Theranostics 9, 868-883

14. Thakur A., Rodríguez-Rodríguez C., Saatchi K., Rose F., Esposito T., Nosrati Z., Andersen P., Christensen D., Hafeli U. O., Foged C., (2018). Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses on Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization. Front. Immunol. 9:2825.

13. Esquinas P., Rodríguez-Rodríguez C., Esposito T., Saatchi K., Celler A., Sossi V., Hafeli U. (2018). Dual SPECT Imaging of In-111 and Ga-67 to simultaneously Determine In Vivo the Pharmacokinetics of Different Radiopharmaceuticals: A Quantitative Tool in Preclinical Research. Phys. Med. Biol. 63, 235029

12. Wang X., Jaraquemada-Peláez M. de G., Rodríguez-Rodríguez C., Cao Y., Buchwalder C., Choudhary N., Jermilova U., Ramogida C. F., Saatchi K., Häfeli U. O., Patrick B. O., Orvig C. (2018) H4octox: Versatile Bimodal Octadentate Acyclic Chelating Ligand for Medicinal Inorganic Chemistry. J. Am. Chem. Soc., 140, 15487-15500

11. Sobol, N., Sutherlin, L., Cedrowska, E., Schorp, J., Rodríguez-Rodríguez, C., Sossi, V., et al. (2018). Synthesis and targeting of gold-coated 177Lu-containing lanthanide phosphate nanoparticles—A potential theranostic agent for pulmonary metastatic disease. APL Bioengineering, 2(1), 016101.

10. Crawford, J. R., Robertson, A. K. H., Yang, H., Rodríguez-Rodríguez, C., Esquinas, P. L., Kunz, P., et al. (2018). Evaluation of 209At as a theranostic isotope for 211At-radiopharmaceutical development using high-energy SPECT. Physics in Medicine & Biology, 63(4), 045025.
9. Schmitt, V., Rodríguez-Rodríguez, C., Hamilton, J. L., Shenoi, R. A., Schaffer, P., Sossi, V., et al. (2018). Quantitative SPECT imaging and biodistribution point to molecular weight independent tumor uptake for some long-circulating polymer nanocarriers. RSC Advances, 8(10), 5586–5595.

8. Thiele, N. A., Brown, V., Kelly, J. M., Coarasa, A. A., Jermilova, U., MacMillan, S. N., et al. (2017). An Eighteen‐Membered Macrocyclic Ligand for Actinium‐225 Targeted Alpha Therapy. Angewandte Chemie International Edition, 56(46), 14712–14717.

7. Buchwalder, C., Rodríguez-Rodríguez, C., Schaffer, P., Karagiozov, S. K., Saatchi, K., Häfeli, U. O. (2017). A new tetrapodal 3-hydroxy-4-pyridinone ligand for complexation of 89zirconium for positron emission tomography (PET) imaging. Dalton Transactions, 46(29), 9654–9663.
6. Esquinas P., Uribe C., Gonzales M., Rodriguez-Rodriguez C., Häfeli U.O., Celler A. (2017). Accuracy of Rhenium-188 SPECT/CT activity quantification for applications in radionuclide therapy using clinical reconstruction methods. Physics in Medicine & Biology 62, 6379-6396
5. Esquinas, P. L., Rodríguez-Rodríguez, C., La Vega, De, J. C., Bokharaei, M., Saatchi, K., Shirmohammad, M., et al. (2017). 188Re image performance assessment using small animal multi-pinhole SPECT/PET/CT system. Physica Medica: European Journal of Medical Physics, 33, 26–37.
4. Robertson, A. K. H., Ramogida, C. F., Rodríguez-Rodríguez, C., Blinder, S., Kunz, P., Sossi, V., & Schaffer, P. (2017). Multi-isotope SPECT imaging of the 225 Ac decay chain: feasibility studies. Physics in Medicine & Biology, 62(11), 4406.

3. Saatchi, K., Tod, S. E., Leung, D., Nicholson, K. E., Andreu, I., Buchwalder, C., Schmitt, V., Häfeli, U. O. (2017). Characterization of Alendronic- and Undecylenic Acid Coated Magnetic Nanoparticles for the Targeted Delivery of Rosiglitazone to Subcutaneous Adipose Tissue. Nanotechnol. Biol. Med. 13(2), 559-568.

2. Esquinas P, Tanguay JF, Gonzalez M, Vuckovic M, Rodriguez-Rodriguez C, Häfeli UO, Celler A (2016). Accuracy, Reproducibility and Uncertainty Analysis of Thyroid Probe-Based Activity Measurements for Determination of Dose Calibrator Settings. Med Phys 43 (12) 6309-6321

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