• Bohrmann, L., Burghardt, T., Rodríguez-Rodríguez, C., Herth, M. M., Saatchi, K., Häfeli, U. O. (2023). Quantitative Evaluation of a Multimodal Aptamer-Targeted Long-Circulating Polymer for Tumor Targeting. ACS Omega, 1–18. http://doi.org/10.1021/acsomega.2c07762

  • Wharton, L., McNeil, S. W., Merkens, H., Yuan, Z., Van de Voorde, M., Engudar, G., Ingham, A., Koniar, H., Rodríguez-Rodríguez, C., Radchenko, V., Ooms, M., Kunz, P., Bénard, F., Schaffer, P., & Yang, H. (2023). Preclinical evaluation of [155/161Tb]Tb-Crown-TATE—A novel SPECT imaging theranostic agent targeting neuroendocrine tumours. Molecules, 28(7), 3155. http://doi.org/10.3390/molecules28073155

  • Wharton, L., Jaraquemada-Peláez, M. de G., Zhang, C., Zeisler, J., Rodríguez-Rodríguez, C., Osooly, M., Radchenko V., Yang H., Lin K-S. , Bénard F., Schaffer P., Orvig C. (2022). H4picoopa─Robust Chelate for 225Ac/111In Theranostics. Bioconjugate Chemistry, 33(10), 1900–1921, http://doi.org/10.1021/acs.bioconjchem.2c00364

  • Esposito, T. V. F., Rodríguez-Rodríguez, C., Blackadar, C., Haney, E. F., Pletzer, D., Hancock, R. E. W., Saatchi, K., Häfeli, U. O. (2022). Biodistribution and toxicity of innate defense regulator 1018 (IDR-1018). European Journal of Pharmaceutics and Biopharmaceutics, 179, 11–25. http://doi.org/10.1016/j.ejpb.2022.08.004

  • Koniar, H., Rodríguez-Rodríguez, C., Radchenko, V., Yang, H., Kunz, P., Rahmim, A., Uribe, C., Schaffer, P. (2022). SPECT imaging of 226Ac as a theranostic isotope for 225Ac radiopharmaceutical development. Physics in Medicine and Biology, 67(18), 185009. http://doi.org/10.1088/1361-6560/ac8b5f

  • Blackadar, C., Choi, K.-Y. G., Embree, M. F., Hennkens, H. M., Rodríguez-Rodríguez, C., Hancock, R. E. W., Saatchi, K., Häfeli, U. O. (2022). SPECT/CT Imaging of 111Ag for the Preclinical Evaluation of Silver-Based Antimicrobial Nanomedicines. ACS Applied Materials & Interfaces, 14, 23, 26382–26393. http://doi.org/10.1021/acsami.2c03609

  • Wharton, L., Zhang, C., Yang, H., Zeisler, J., Radchenko, V., Rodríguez-Rodríguez, C., Ossoly, M., Patrick, O.B., Lin K-S. , Bénard F., Schaffer P., Orvig C. (2022). [213Bi]Bi3+/[111In]In3+-neunpa-cycMSH: Theranostic Radiopharmaceutical Targeting Melanoma─Structural, Radiochemical, and Biological Evaluation. Bioconjugate Chemistry, 33(3), 505–522. http://doi.org/10.1021/acs.bioconjchem.2c00038

  • Wharton, L., Zhang, C., Zeisler, J., Rodríguez-Rodríguez, C., Osooly, M., Radchenko V., Yang H., Lin K-S. , Bénard F., Schaffer P., Orvig C. (2022). H3TPAN-Triazole-Bn-NH2: Tripicolinate Clicked-Bifunctional Chelate for [225Ac]/[111In] Theranostics. Bioconjugate Chem., 33, 12, 2381–2397. http://doi.org/10.1021/acs.bioconjchem.2c00465

  • Engudar, G., Rodríguez-Rodríguez, C., Mishra, N. K., Bergamo, M., Amouroux, G., Jensen, K. J., Saatchi, K., Häfeli, U. O. (2022). Metal-ion coordinated self-assembly of human insulin directs kinetics of insulin release as determined by preclinical SPECT/CT imaging. Journal of Controlled Release : Official Journal of the Controlled Release Society, 343, 347–360. http://doi.org/10.1016/j.jconrel.2022.01.032

 

  • Nosrati, Z., Esquinas, P. L., Rodríguez-Rodríguez, C., Tran, T., Maharaj, A., Saatchi, K., Häfeli, U. O. (2021). Simultaneous SPECT imaging with 123I and 125I – a practical approach to assessing a drug and its carrier at the same time with dual imaging. International Journal of Pharmaceutics, 606, 120884. http://doi.org/10.1016/j.ijpharm.2021.120884

  • Wu, L., Wu, L.-P., Wu, J., Sun, J., He, Z., Rodríguez-Rodríguez, C., Saatchi, K., Dailey, L.A., Häfeli, U. O., Dongmei C., Mingshi, Y. (2021). Poly(lactide-co-glycolide) Nanoparticles Mediate Sustained Gene Silencing and Improved Biocompatibility of siRNA Delivery Systems in Mouse Lungs after Pulmonary Administration, ACS Applied Materials & Interfaces. 13, 3722 – 3737, http://doi.org/10.1021/acsami.0c21259

  • Esposito, T. V. F., Stütz, H., Rodríguez-Rodríguez, C., Bergamo, M., Charles, L., Geczy, R., Saatchi, K., Häfeli, U. O. (2021). Preparation of Heat-Denatured Macroaggregated Albumin for Biomedical Applications Using a Microfluidics Platform. ACS Biomaterials Science & Engineering, 7(6), 2823–2834. http://doi.org/10.1021/acsbiomaterials.1c00284

  • Suárez-García, S., Esposito, T. V. F., Neufeld-Peters, J., Bergamo, M., Yang, H., Saatchi, K., Schaffer, P., Häfeli, U. O., Ruiz-Molina, D.*, Rodríguez-Rodríguez, C.*, Novio, F.* (2021). Hybrid Metal–Phenol Nanoparticles with Polydopamine-like Coating for PET/SPECT/CT Imaging. ACS Applied Materials & Interfaces. 13, 10705-10718 http://doi.org/10.1021/acsami.0c20612
  • Nosrati, Z., Bergamo, M., Rodríguez-Rodríguez, C., Saatchi, K., & Häfeli, U. O. (2020). Refinement and validation of infrared thermal imaging (IRT): a non-invasive technique to measure disease activity in a mouse model of rheumatoid arthritis, 1–16. http://doi.org/10.1186/s13075-020-02367-w

  • Kalomoiri, P., Rodríguez-Rodríguez, C., Sørensen, K. K., Bergamo, M., Saatchi, K., Häfeli, U. O., & Jensen, K. J. (2020). Bioimaging and Biodistribution of the Metal-Ion-Controlled Self-Assembly of PYY3-36 Studied by SPECT/CT. Chembiochem : a European Journal of Chemical Biology, 248. http://doi.org/10.1002/cbic.202000266

  • Yang, H., Zhang, C., Yuan, Z., Rodríguez-Rodríguez, C., Robertson, A., Radchenko, V., et al. (2020). Synthesis and Evaluation of a Macrocyclic Actinium-225 Chelator, Quality Control and In Vivo Evaluation of 225 Ac-crown-αMSH Peptide. Chemistry (Weinheim an Der Bergstrasse, Germany), 26(50), 11435–11440. http://doi.org/10.1002/chem.202002999

  • Wang, X., Jaraquemada-Peláez, M. de G., Cao, Y., Ingham, A., Rodríguez-Rodríguez, C., Pan, J., et al. (2020). H2CHXhox: Rigid Cyclohexane-Reinforced Nonmacrocyclic Chelating Ligand for [nat/67/68Ga]Ga3. Inorganic Chemistry, 59(7), 4895–4908. http://doi.org/10.1021/acs.inorgchem.0c00168

  • Agnoletti, M., Rodríguez-Rodríguez C., Klodzinska, S.N., Esposito, T.V.F., Saatchi, K., Nielsen, H. M., Hafeli, U.O.(2020) Monosized Polymeric Microspheres Designed for Passive Lung Targeting: Biodistribution and Pharmacokinetics after Intravenous Administration. ACS Nano, 14, 6693-6706
  • Wu, L., Rodríguez-Rodríguez C., Cun, D., Yang, M., Saatchi, K., & Hafeli, U. O. (2020). Quantitative comparison of three widely-used pulmonary administration methods in vivo with radiolabeled inhalable nanoparticles.European Journal of Pharmaceutics and Biopharmaceutics, 152, 108-115. http://doi.org/10.1016/j.ejpb.2020.05.004
  • Tran, T., Bønløkke, P., Rodríguez-Rodríguez C., Nosrati, Z., Esquinas, P. L., Borkar, N., et al. (2020).Using in vitro lipolysis and SPECT/CT in vivo imaging to understand oral absorption of fenofibrate from lipid-based drug delivery systems. Journal of Controlled Release : Official Journal of the Controlled Release Society, 317, 375-384. http://doi.org/10.1016/j.jconrel.2019.11.024
  • Buchwalder, C., Jaraquemada-Peláez, M. de G., Rousseau, J., Merkens, H., Rodríguez-Rodríguez C., Orvig, C., et al. (2019). Evaluation of the Tetrakis(3-Hydroxy-4-Pyridinone) Ligand THPN with Zirconium(IV): Thermodynamic Solution Studies, Bifunctionalization, and in Vivo Assessment of Macromolecular 89Zr-THPN-Conjugates. Inorganic Chemistry 58(21), 14667-14681. http://doi.org/10.1021/acs.inorgchem.9b02350
  • Ramogida, C. F., Robertson, A. K. H., Jermilova, U., Zhang, C., Yang, H., Kunz, P., et al. (2019). Evaluation of polydentate picolinic acid chelating ligands and an α-melanocyte-stimulating hormone derivative for targeted alpha therapy using ISOL-produced 225Ac,1-20. http://doi.org/10.1186/s41181-019-0072-5
  • de la Vega J, Esquinas PL, Rodriguez-Rodriguez C, Bokharaei M, Moskalev I, Liu D, Saatchi K, Hafeli UO (2019). Radioembolization of Hepatocellular Carcinoma with Built-In Dosimetry: First In Vivo Results with Uniformly-Sized, Biodegradable Microspheres Labeled with 188Re. Theranostics 9, 868-883
  • Thakur A., Rodríguez-Rodríguez C., Saatchi K., Rose F., Esposito T., Nosrati Z., Andersen P., Christensen D., Hafeli U. O., Foged C., (2018). Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses on Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization. Front. Immunol. 9:2825.
  • Esquinas P., Rodríguez-Rodríguez C., Esposito T., Saatchi K., Celler A., Sossi V., Hafeli U. (2018). Dual SPECT Imaging of In-111 and Ga-67 to simultaneously Determine In Vivo the Pharmacokinetics of Different Radiopharmaceuticals: A Quantitative Tool in Preclinical Research. Phys. Med. Biol. 63, 235029
  • Wang X., Jaraquemada-Peláez M. de G., Rodríguez-Rodríguez C., Cao Y., Buchwalder C., Choudhary N., Jermilova U., Ramogida C. F., Saatchi K., Häfeli U. O., Patrick B. O., Orvig C. (2018) H4octox: Versatile Bimodal Octadentate Acyclic Chelating Ligand for Medicinal Inorganic Chemistry. J. Am. Chem. Soc., 140, 15487-15500
  • Sobol, N., Sutherlin, L., Cedrowska, E., Schorp, J., Rodríguez-Rodríguez, C., Sossi, V., et al. (2018). Synthesis and targeting of gold-coated 177Lu-containing lanthanide phosphate nanoparticles—A potential theranostic agent for pulmonary metastatic disease. APL Bioengineering, 2(1), 016101.
  • Crawford, J. R., Robertson, A. K. H., Yang, H., Rodríguez-Rodríguez, C., Esquinas, P. L., Kunz, P., et al. (2018). Evaluation of 209At as a theranostic isotope for 211At-radiopharmaceutical development using high-energy SPECT. Physics in Medicine & Biology, 63(4), 045025.
  • Schmitt, V., Rodríguez-Rodríguez, C., Hamilton, J. L., Shenoi, R. A., Schaffer, P., Sossi, V., et al. (2018). Quantitative SPECT imaging and biodistribution point to molecular weight independent tumor uptake for some long-circulating polymer nanocarriers. RSC Advances, 8(10), 5586–5595.
  • Thiele, N. A., Brown, V., Kelly, J. M., Coarasa, A. A., Jermilova, U., MacMillan, S. N., et al. (2017). An Eighteen‐Membered Macrocyclic Ligand for Actinium‐225 Targeted Alpha Therapy. Angewandte Chemie International Edition, 56(46), 14712–14717.
  • Buchwalder, C., Rodríguez-Rodríguez, C., Schaffer, P., Karagiozov, S. K., Saatchi, K., Häfeli, U. O. (2017). A new tetrapodal 3-hydroxy-4-pyridinone ligand for complexation of 89zirconium for positron emission tomography (PET) imaging. Dalton Transactions, 46(29), 9654–9663.
  • Esquinas P., Uribe C., Gonzales M., Rodriguez-Rodriguez C., Häfeli U.O., Celler A. (2017). Accuracy of Rhenium-188 SPECT/CT activity quantification for applications in radionuclide therapy using clinical reconstruction methods. Physics in Medicine & Biology 62, 6379-6396
  • Esquinas, P. L., Rodríguez-Rodríguez, C., La Vega, De, J. C., Bokharaei, M., Saatchi, K., Shirmohammad, M., et al. (2017). 188Re image performance assessment using small animal multi-pinhole SPECT/PET/CT system. Physica Medica: European Journal of Medical Physics, 33, 26–37.
  • Robertson, A. K. H., Ramogida, C. F., Rodríguez-Rodríguez, C., Blinder, S., Kunz, P., Sossi, V., & Schaffer, P. (2017). Multi-isotope SPECT imaging of the 225 Ac decay chain: feasibility studies. Physics in Medicine & Biology, 62(11), 4406.
  • Saatchi, K., Tod, S. E., Leung, D., Nicholson, K. E., Andreu, I., Buchwalder, C., Schmitt, V., Häfeli, U. O. (2017). Characterization of Alendronic- and Undecylenic Acid Coated Magnetic Nanoparticles for the Targeted Delivery of Rosiglitazone to Subcutaneous Adipose Tissue. Nanotechnol. Biol. Med. 13(2), 559-568.
  • Esquinas P, Tanguay JF, Gonzalez M, Vuckovic M, Rodriguez-Rodriguez C, Häfeli UO, Celler A (2016). Accuracy, Reproducibility and Uncertainty Analysis of Thyroid Probe-Based Activity Measurements for Determination of Dose Calibrator Settings. Med Phys 43 (12) 6309-6321
  • Walker, M., Goorden, M., Dinelle K., Ramakers R., Blinder S., Shirmohammad M., van der Have F., Beekman F., Sossi V.. (2014). Performance Assessment of a Preclinical PET Scanner with Pinhole Collimation by Comparison to a Cincidence-Based Small-Animal PET Scanner. J. Nucl. Med. 55(8) 1368-1374.