188Re Image Performance Assessment
Over the last several years, 188Re has arisen interest in Nuclear Medicine due to its physical and chemical properties. From the Physics perspective, 188Re (t1/2 = 17 h) decays into an excited state of 188Os by emission of β-particles with maximum energy of 2.1 MeV, making it suitable for radionuclide therapies. In addition, 15%-abundant photons (155 keV) are emitted after de-excitation of the daughter nucleus allowing to image the bio-distribution of 188Re using SPECT and performing accurate dosimetry calculations. From a chemical perspective, 188Re shows a rich coordination chemistry and a close resemblance to -its group congener- 99mTc. The goal of this study is to investigate 188Re image quality and image quantification in VECTor/CT by performing a series of phantom experiments using different collimators.